Executive producers Robert Rovner and Jessica Queller announced Cryer's casting opposite Melissa Benoist's titular heroine in The CW series on Friday.
"We are enormous fans of Jon Cryer, and he was instantly our dream actor to play the iconic role of Lex Luthor. Jon is a super-talent, and the fact that he played Lenny Luthor in 'Superman IV' brings an added layer of legacy to his casting," they said in a joint statement.
"We're beyond thrilled to welcome Jon to the Supergirl family."
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