Director Park Chan-wook is to begin helming the six-part adaptation of John le Carre's spy novel in early 2018.
Florence Pugh is to co-star in the project, which is set in the 1970s.
"To play an enigmatic man who hides his true feelings deep inside, I couldn't think of a more fitting actor. I believe Skarsgard's growing depth as a great character actor and his soaring energy will elevate 'The Little Drummer Girl' to a high place," Park Chan-wook said in a statement Tuesday.
The story follows an actress who meets an Israeli intelligence officer and gets entangled "in a complex and high-stakes plot," a synopsis said.
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