The 61-year-old supermodel wed fiance Dr. Robert "Rocky" Gerner on Saturday afternoon, Entertainment Tonightreported.
Dickinson and Gerner exchanged vows in an intimate ceremony at her friend Suzan Hughes' Beverly Hills home.
"I am so delighted, ecstatic, over the moon, out of body, a runaway bride," Dickinson told ET just before saying "I do."
"When Rocky first introduced himself to me, I felt like I had seen a unicorn, a one of a kind. He's the brightest and the best and the funniest and the most exciting man I've ever met in my life."
Dickinson's wedding featured pale pink, green and ivory colors. She reportedly donned a Jane Booke gown down the aisle and broke down in tears halfway through saying her vows.
The wedding singer, Crown Jwlz, performed "You Don't Own Me" as the couple's wedding song.
At the reception, guests enjoyed grilled chicken skewers with spinach almond pesto, assorted mini quiche Lorraine, tea sandwiches, salads, heirloom tomato puff pastry tarts and a full bar. The three-tiered wedding cake boasted red velvet, chocolate fudge and vanilla.
Gerner apparently helped Dickinson, who also starred in The Janice Dickinson Modeling Agency, through her breast cancer battle.
"Today I am finally over the hump and the fright for myself and my family from the most horrible word in the world, cancer," Dickinson recently revealed to ET while shopping for her wedding dress.
"I've been reborn and the days are much bluer, the clouds are much brighter, roses smell rosier, and I finally heard from my betrothed that we are going to do this now, we will be tying the knot this year."
Dickinson served as a judge on Top Model's first four editions before she was replace by Lesley "Twiggy" Lawson for Season 5. The Janice Dickinson Modeling Agency then premiered in 2006 and ran for four seasons.
She also appeared on Celebrity Rehab with Dr. Drew's fourth season and The Surreal Life.