Angela Shapiro-Mathes' short stint as TLC's president has come to a close.

Shapiro-Mathes left her position at the Discovery Communications-owned cable network after just 15 months on the job, The Hollywood Reporter reported Friday, adding sources claimed Discovery was unhappy with TLC's "creative direction."

"My thanks to Angela for her hard work, leadership and passion over the past year," Discovery president David Zaslav told The Reporter.  "She has diversified TLC's programming mix and increased the network's development presence in Los Angeles."

Shapiro-Mathes replaced David Abraham at TLC in April 2007 and subsequently oversaw the network's re-branding effort earlier this year. 

It focused on TLC's "real-life" content and included both new and returning programs packaged into nights themed around subject matter geared towards the home viewing audience and advertisers.  In addition, she also shifted the network's programming operations from Discovery's headquarters in Silver Springs, MD to Los Angeles.

However TLC failed to produce a breakout hit during Shapiro-Mathes' term and sources told The Reporter some of the network's resources will likely move back to Maryland "to regain efficiencies that come with having multiple channels under one roof."

Shapiro-Mathes will be replaced by Eileen O'Neill, who served as TLC's interim general manager between Abraham and Shapiro-Mathes, according to The Reporter.  Most recently O'Neill had helmed Discovery's newly launched Planet Green network, which will now be run by Clark Bunting.

Prior to her Planet Green and interim TLC roles, O'Neill served as general manager of Discovery's Fit TV and Discovery Health networks.  While running Discovery Health she developed Jon & Kate Plus 8, which now ranks as TLC's top-rated series.  (After airing its first two seasons on Discovery Health, Jon & Kate Plus 8 moved over to TLC earlier this year.)