"The Office" star Steve Carell topped off a big year Monday night, winning the Golden Globe for best actor in a TV comedy.

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Carell, who catapulted to fame with his big screen performance in "The 40-year-old Virgin," poked gentle fun at his wife, Nancy, in his acceptance speech for his role at the top of the NBC ensemble comedy.

The Golden Globe for best actress in a TV comedy went to the only nominee not on ABC's "Desperate Housewives" -- Mary Louise Parker of Showtime's "Weeds."

Oscar favorite Reese Witherspoon won the Golden Globe for best actress in a film musical or comedy for her role as June Carter Cash in the Johnny Cash biopic, "Walk the Line."

"My husband just hit me so hard, I almost fell over," she said. "I was having a lot of fun, but I'm having even more fun now."

She said the movie was important to her personally because it's "about where I grew up and the music I grew up listening to."

HBO's star-studded miniseries "Empire Falls" won the Golden Globe Award for best TV miniseries or made-for-TV motion picture.