The city's historic committee said they are considering recommending a name change for Old Slave Road in Wildwood, Mo.
The private street has six homes on it and runs by a historic cemetery, The Post-Dispatch reported.
Lynne Martin, the chairman of the Historic Preservation Commission, said the name is a misnomer and slaves never used the road.
Those that live on the road said the name may offend people and discourage them from living on it, The Post-Dispatch said.
The property owners are recommending naming the road Elijah Madison Lane in honor of a former slave who grew up in the area and served in a segregated unit during the Civil War.
But others say the change is an effort to sanitize history and stigmatize the word slave, The Post-Dispatch said.
"I couldn't disagree more," Esley Hamilton, a preservation historian said. "We should not allow the word 'slave' to be stigmatized any more than we should allow the word 'Jew' to be used in that way."