The big-screen blockbuster "Inception" picked up six prizes, including the top honor, The Ultimate Scream, at Spike TV's Scream 2010 awards show in Las Vegas.

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Writer-director Christopher Nolan's psychological science-fiction thriller earned the awards for Best Science Fiction Actor for Leonardo DiCaprio, Best Supporting Actor for Joseph Gordon-Levitt and Breakout Performance for Tom Hardy. It also won the Fight Scene of the Year and Best Science Fiction Movie awards.

"Zombieland" won the prizes for Best Horror Film, Best Ensemble and Best Cameo, the latter of which was won by a scene-stealing Bill Murray.

His "Ghostbusters" leading lady, Sigourney Weaver, was named Ultimate Scream Heroine, while her "Aliens" and "Avatar" director, James Cameron, won the Best Director honor and "Avatar" the Best 3D movie title.

"Green Lantern" won the award for Most Anticipated Movie, with star Ryan Reynolds accepting the award.

The event was taped at the Greek Theatre Sunday and will be aired on Spike TV Tuesday.