The celebrity magazine says the couple exchanged vows in Beverly Hills, Calif., Saturday night in front of 100 guests including Moore's ex-husband, Bruce Willis.
Reps for the newlyweds declined comment, US Weekly said.
The brief, traditional ceremony at a private mansion was a formal affair, a source told the magazine.
It is the third marriage for Moore, 42, and the first for Kutcher, 27.
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