"Khloe and Lamar are absolutely not getting divorced," Jenner told E! News. "There's been no talk of divorce."
Recent headlines have claimed the couple has been living apart and Kardashian has had enough with alleged accounts of Odom's infidelity. According to reports, Odom has cheated on Kardashian numerous times during their marriage -- one of which was an alleged extensive affair that lasted for months.
"Things are really good with Lamar" although he's "so sensitive" to all the negative publicity surrounding their union, Kardashian told E! News in January.
That same month, Kardashian took to her official website and expressed her frustration with tabloids reporting inaccurate details regarding the status of her marriage among many other "false stories" about her family.
"It is a complete waste of time to address these reports every time they print these ridiculous and absurd tabloid stories," she wrote in a blog posting.
"Anyone who pays attention to these things can easily see the incredible bond that everyone in my family shares. I'm happily married to a wonderful man and fall in love with him more and more each day, and we'll have a baby when god wants us to and when the time is right. These blatant lies are distasteful and shameless."
Kardashian and Odom wed in September 2009 at a private estate in Beverly Hills.