Grey's Anatomy is an American television medical drama that premiered on the American Broadcasting Company (ABC), as a mid-season replacement on March 27, 2005. The series has aired nine seasons, and focuses on the fictional lives of surgical interns and residents, as they gradually evolve into seasoned doctors, while trying to maintain personal lives. The show's premise originated with Shonda Rhimes, who serves as an executive producer, along with Betsy Beers, Mark Gordon, Krista Vernoff, Rob Corn, Mark Wilding, and Allan Heinberg. The series was created to be racially diverse, utilizing a color-blind casting technique. It is primarily filmed in Los Angeles, California.
The series' protagonist is Dr. Meredith Grey (Ellen Pompeo), who originally is accepted into the residency program at the fictional Seattle Grace Hospital. Meredith is assigned to work under Dr. Miranda Bailey (Chandra Wilson), along with Dr. Cristina Yang (Sandra Oh), Dr. George O'Malley (T. R. Knight), Dr. Izzie Stevens (Katherine Heigl), and Dr. Alex Karev (Justin Chambers). Following O'Malley's death and Stevens' departure, the hospital's merger with Mercy West brings in Dr. Jackson Avery (Jesse Williams) and Dr. April Kepner (Sarah Drew), in the sixth season. The surgical wing is primarily supervised by Dr. Richard Webber (James Pickens, Jr.), who is eventually replaced by Dr. Derek Shepherd (Patrick Dempsey), and later Dr. Owen Hunt (Kevin McKidd).