The new teaser brings together several characters in the multiverse. Carter (Atwell) is seen leading an alternate version of the Avengers, while Strange (Cumberbatch) faces off with his evil counterpart.
"Why stop at one hero when we can show you all of them?" Michael Rooker says as Yondu in a voiceover.
Disney+ said the remaining episodes will bring together "the biggest heroes of the multiverse as they navigate alternate realities on a collision course toward an unforgettable finale."
What If...? is written and created by A.C. Bradley and directed by Bryan Andrews. The series returns with a new episode Wednesday on Disney+.
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