Rosie O'Donnell took to Twitter to respond to Donald Trump's Republican presidential debate comment referring to her as a "fat pig" and other demeaning labels.

"Try explaining that 2 ur kids," the former View panel member wrote minutes after Trump's diss.

The incident occurred when Trump cut GOP debate mediator Megyn Kelly off as she confronted him about sexist comments he made in the past.

"You've called women you don't like 'fat pigs,' 'dogs,' 'slobs' and 'disgusting animals,'" she said before Trump chimed in with a raised finger.

"Only Rosie O'Donnell," he said before the crowd's boisterous reaction.

"No it wasn't," she shot back.

"For the record, it was well beyond Rosie O'Donnell. Your Twitter account has several disparaging comments about women's looks. You once told a contestant on 'Celebrity Apprentice' it would be a pretty picture to see her on her knees. Does that sound to you like the temperament of a man we should elect as president?"

Trump responded with a quick jab to political correctness, expressing that it was a "big problem this country has."

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"I don't frankly have time for total political correctness," he said.