Filming on the series is to begin shooting in September at the new Wolf Studios in Wales and on location in Oxford. It will air on Sky 1 and NOW TV.
Juan Carlos Medina is directing from a script by Kate Brooke, who will also serve as show-runner.
"Teresa and Matthew perfectly capture my characters -- I'm so excited by the casting and how they will bring the books to life," author and executive producer Deborah Harkness said in a statement Tuesday.
"The show is a relationship drama, grounded in emotional truth. Diana and Matthew, like all couples who meet and fall in love, at times struggle to understand each other and come to terms with their differences. And if you're a vampire and a witch -- those differences are huge," Brooke added.
Anne Mensah, Sky's head of drama, remarked: "'A Discovery of Witches' is a proper love story for grown-ups. However, the fact that it also examines science, magic and being 'other' in the modern world makes it a must watch."
"Deborah Harkness and Kate Brooke have given us a drama that packs both an emotional and thought-provoking punch. With the breathtaking vision of director Juan Carlos Medina and the Bad Wolf team, I feel very confident we are offering our customers something truly magical."
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