Lamar Odom's condition has taken a dramatic turn for the better.

Odom has woken from the coma he had slipped into following a drug overdose on Tuesday and is communicating.

Odom opened his eyes and spoke to estranged wife Khloe Kardashian on Friday morning, Kardashian's mother Kris Jenner told Access Hollywood's Billy Bush. Kardashian has maintained a bedside vigil since Odom was transported to a Las Vegas hospital on Tuesday.

Doctors are now attempting to wean Odom off a ventilator and onto a breathing mask, according to Jenner, however he reportedly remains in very critical condition and the damage to several vital organs is serious.

According to E! News, Odom saw Kardashian when he opened his eyes, said  "Hey, baby," and gave her a thumbs up before returning to sleep.

Although Odom and Kardashian signed divorce paperwork in July, they are still legally married. As a result, the Keeping Up with the Kardashians star has been making all of Odom's medical decisions for him.

"Khloe is distraught," a source told Us Weekly. "She has barely slept since Tuesday. She is extremely emotional. She's very protective of Lamar. And she's inconsolable."

Odom was found unconscious in a Nevada brothel on Tuesday after a weekend of partying. Cocaine, opiates and "herbal Viagra" were all discovered in his system, and according to reports, he suffered several strokes.

In the 911 call that was released by authorities, a woman at the brothel said Odom had "blood coming from his nose and mouth along with a white substance."

Odom currently has family and friends at his side, including his ex Liza Morales and two kids, Destiny and Lamar Jr. Kardashian allegedly footed the bill for his father and children's travel expenses.