After starring on the Bravo reality series for five seasons, Dubrow, 48, has announced her show departure.
"After a lot of careful thought and deliberation, I have decided not to return to RHOC this season. These past 5 years have been an incredible journey and I'm so proud to have been a part of such an iconic piece of pop culture," Dubrow told Bravo in a statement.
"I am so grateful to Evolution Media, Bravo and the whole NBCU family for all of the incredible experiences and the opportunities RHOC has afforded me and my family. However, at this point in my life, I have decided to go in another direction and do what's best for my family and career."
Dubrow, however, may come back in the future or at least be open to cameos on the series.
"Should I change my mind, I thank Andy Cohen, Evolution and Bravo for telling me that the door is always open," she said.
Dubrow, the wife of Botched star Dr. Terry Dubrow, joined The Real Housewives franchise back in 2009 for Season 7. She has four children with Terry -- 12-year-old twins Nicholas and Maximillia, 9-year-old Katarina, and 5-year-old Collette.
Dubrow elaborated on her decision to exit The Real Housewives of Orange County in her PodcastOne show called Heather Dubrow's World.
"It wasn't an easy decision," the reality TV star admitted. "I felt like I was at a tipping point, and just... it was time. But, it's all positive and I wish them all the best... I will miss the girls."
Edmonds, a 32-year-old Missouri native who welcomed her first child in November, joined the The Real Housewivesfranchise as a full-time cast member in Season 10. She resumed her role on Season 11, which just wrapped in November 2016.
Dubrow and Edmonds starred on the last season of The Real Housewives of Orange County with Vicki Gunvalson, Tamra Judge, Shannon Beador, and Kelly Dodd.
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Judge hinted she will return for Season 12 when she posted an Instagram photo of herself on Monday wearing a trucker hat that read "Housewife" with the following caption: "Stillahousewife." Gunvalson and Dodd are reportedly not happy she'll be coming back to due past unresolved conflicts.