ABC's "Grey's Anatomy" star Katherine Heigl will be the first Hollywood celebrity to appear on the cover of Prevention magazine.

The actress who plays Dr. Isobel "Izzie" Stevens in the popular medical drama will be the subject of a cover story in Prevention's May issue about organ donation, the New York Post reported Wednesday.

Heigl's older brother, Jason, was thrown from the back of a pickup truck and declared brain dead at age 15, the Post said. His organs were donated by the family.

"Jason didn't need them any more and it's what he would have wanted," Heigl said in Prevention.