George Clooney says "ER" prepared him to become a father to twins.

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The 55-year-old actor joked in an interview with E! News that his role as pediatrician Doug Ross on the NBC medical drama prepped him to welcome kids with wife Amal Clooney.

"I played a pediatrician on 'ER,' so I know how to work on extra children," he quipped. "If there's any accidents, I'm there."

Julie Chen announced on "The Talk" in February that Amal is pregnant and expecting twins in June.

Clooney, who spoke to E! while promoting his movie "Suburbicon" at CinemaCon, said he is thrilled to become a parent.

"Can you believe it? [I'm] even happier [than before]," he gushed. "I didn't know that we'd have kids. I was very happy that we were going to get married and then [a pregnancy] seemed like the next step."

Clooney married Amal in Venice, Italy, in September 2014 after less than a year of dating.

He gave an update on the 39-year-old human rights lawyer an interview with "Extra" at the convention.

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"She is doing really great. She's amazing. I don't have anything to do. There is nothing I can do to help, but make tea and stuff," the star said.

Clooney starred as Dr. Ross in Seasons 1 through 5 of "ER," and appeared in Seasons 6 and 15.

He directed Matt Damon, Oscar Isaac, Josh Brolin and Julianne Moore in "Suburbicon," which opens in theaters Nov. 3.