Directed by James Macdonald, the limited engagement of the play is scheduled to begin previews Dec. 27, with an official opening planned for Broadway on Jan. 24.
"Opposites attack in Sam Shepard's Pulitzer Prize-nominated play about two brothers with more in common than they think. Holed up in their mother's California house, screenwriter Austin and lowlife Lee wrestle with big issues -- and each other," a news release said.
"Order vs. chaos. Art vs. commerce. Typewriter vs. toaster... Shepard's rip-roaring classic returns to Broadway, gleefully detonating our misguided myths of family, identity and the American Dream."
Hawke previously acted alongside Dano in the film "Taking Lives" and directed him on stage in "Things We Want."
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