The show was planned to raise money for various schools and outreach programs for Autistic children, USA Today reported.
Comedian and cartoonist Robert Smigel, best known for his alter-ego Triumph the Insult Comic Dog, organized the event. His son Daniel is Autistic.
USA Today said a similar special, which aired in 2006, earned nearly $3 million.
Comedian Sarah Silverman told the newspaper Smigel "makes the whole thing happen."
"And it's all people I know from different parts of my life. It's like a family reunion," she said.
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