Ryan Seacrest has been booked as host of the two-day iHeartRadio Music Festival, Clear Channel Radio announced.

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Billed as the biggest live concert festival in radio history, the event boasts a lineup that includes Lady Gaga, Coldplay, Alicia Keys, Steven Tyler, The Black Eyed Peas, Kenny Chesney, Jennifer Lopez, Carrie Underwood, Jane's Addiction, Nicki Minaj, John Mayer, David Guetta, Rascal Flatts, Bruno Mars, Kelly Clarkson and Sublime with Rome. Promoters say there will be special performances by Usher and Sting.

The artists are to appear on one stage at the MGM Grand in Las Vegas on consecutive nights -- Sept. 23-24.

The event was scheduled to celebrate the official start-up of the expanded iHeartRadio, Clear Channel's free digital radio product, which the company said will combine its more than 750 broadcast radio and digital-only stations from 150 cities with the ability to create custom stations.

"Music is the heart of our business and we think there is no better way to celebrate the launch of the new iHeartRadio than with a groundbreaking, multi-day festival featuring the world's biggest, most exciting artists -- and reaching the largest combined U.S. radio and online audience ever," Bob Pittman, chairman of media and entertainment platforms for Clear Channel Radio, said in a statement Monday.

"The new iHeartRadio will offer users a much broader, more integrated and customized digital listening experience than any other service available -- and it's all in one product."