Based on the book of the same name, the film depicts the true story of Henrietta Lacks whose cells were used without permission to create the first immortal human cell line which led to unprecedented breakthroughs that changed the face of medicine.
The clip, released Wednesday, follows Lacks' daughter Deborah (Winfrey) as she learns of what happened to her mother alongside journalist Rebecca Skloot (Byrne) who writes the book on their findings.
"Hope I don't regret this," Winfrey says after she agrees to Byrne writing the book.
"Science took her cells. Her family reclaimed her story," notes HBO in the synopsis.
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