"It's a dream come true for Sheldon when he has a close encounter with his hero, Mr. Spock," a synopsis said.
Nimoy's voice will be heard as his iconic "Star Trek" character in the March 29 episode of the show.
"For this episode, we are delighted to hear his voice. We look forward to introducing Mr. Nimoy, body part by body part, over the course of many seasons to come," Executive Producer Bill Prady said in a statement.
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