The Web site said Aniston's looks are complemented by an appealing personality that seems to draw people to her.
"Funny is sexy, and Jennifer Aniston is funny," the Web site said in a written statement. "Her down-to-earth persona makes her seem attainable."
The Detroit Free Press noted Angelina Jolie, who came in at No. 10, has been in a relationship with Aniston's ex-husband, Brad Pitt, for six years.
As for Aniston, she told US Magazine that French star Brigitte Bardot and feminist writer Gloria Steinem would have gotten her vote. "If I had to choose one, I'd say Gloria because, well, she's the full package," Aniston said. "That's sexy."