The series is based on a one-hour special that aired on E! last month and was also titled Holly's World.
"Audiences fell in love with Holly on E! and fans are eager to follow her next chapter," said network programming executive Lisa Berger. "The series will feature Holly and her family of friends as they take on new loves, careers and ambitions together."
Holly's World will document various aspects of Madison's life -- including her starring role in Vegas' Peepshow stage show, traveling to Mexico for a calendar shoot, getting involved in local politics, and maintaining a busy social life.
Madison appeared in the first five seasons of E!'s The Girls Next Door -- along with Bridget Marquardt and Kendra Wilson -- as one of Hefner's girlfriends.