Garces is best known for her work in the Harold & Kumar film franchise.
The re-boot of "All My Children," which was canceled by ABC in 2011, is to begin airing April 29 on Hulu, Hulu Plus and iTunes thanks to The Online Network.
Garces will portray Lea Marquez, "a smart, savvy, beautiful woman who's devoted her life to a career of fighting crime and bringing down the bad guys," the network said.
"Lea's career takes up most of her days and nights, which leaves little time for a personal life. That is, until a man challenges her safe, controlled existence and threatens to open up the part of her she'd long since put to rest, her heart."